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Contact details +6492127050

Dr Kaio Vitzel

Senior Lecturer in Physiology

Doctoral Supervisor
School of Health Sciences

Professional

Certifications and Registrations

  • Licence, Supervisor, Ƶ

Research Expertise

Research Interests

From skeletal muscle molecular biology and biochemistry to muscle metabolism, contractile activity and its influence on whole body function: energy metabolism, hypertrophy/atrophy, regeneration, oxidative stress, contractile function/exercise, diabetes, nutritional supplementation, stem cells treatment and applied exercise physiology.

Thematics

Health and Well-being

Area of Expertise

Field of research codes
Biochemistry and Cell Biology (060100): Biological Sciences (060000): Cell Metabolism (060104):
Exercise Physiology (110602): Human Movement and Sports Science (110600): Medical And Health Sciences (110000):
Physiology (060600)

Keywords

Skeletal muscle metabolism

Control of muscle mass and regeneration

Exercise physiology

Research Outputs

Journal

Marzuca-Nassr, GN., Peñailillo, L., Valladares-Ide, D., Martinez-Huenchullan, S., Curi, R., Hirabara, SM., . . . Vitzel, KF. (2023). Editorial: Spotlight on aging: physiology, prevention, and management of skeletal muscle atrophy. Frontiers in Physiology. 14
[Journal article]Authored by: Vitzel, K.
Rodrigues Junior, CF., Murata, GM., Gerlinger-Romero, F., Nachbar, RT., Marzuca-Nassr, GN., Gorjão, R., . . . Curi, R. (2023). Changes in Skeletal Muscle Protein Metabolism Signaling Induced by Glutamine Supplementation and Exercise. Nutrients. 15(22)
[Journal article]Authored by: Vitzel, K.
Peeters, WM., Gram, M., Dias, GJ., Vissers, MCM., Hampton, MB., Dickerhof, N., . . . Rowlands, DS. (2023). Changes to insulin sensitivity in glucose clearance systems and redox following dietary supplementation with a novel cysteine-rich protein: A pilot randomized controlled trial in humans with type-2 diabetes. Redox Biology. 67
[Journal article]Authored by: Dickens, M., Hodges, L., Perry, B., Rowlands, D., Vitzel, K.
Scervino, MVM., Fortes, MAS., Vitzel, KF., de Souza, DR., Murata, GM., Santana, GO., . . . Curi, R. (2023). Autophagy signaling in hypertrophied muscles of diabetic and control rats. FEBS Open Bio. 13(9), 1709-1722
[Journal article]Authored by: Vitzel, K.
Hirabara, SM., Gorjao, R., Marzuca-Nassr, GN., Vitzel, KF., Vinolo, MAR., & Masi, LN. (2023). Editorial: Molecular and cellular mechanisms involved in inflammation, metabolism and oxidative stress induced by coronaviruses. Frontiers in Microbiology. 14
[Journal article]Authored by: Vitzel, K.
Silva-Gutiérrez, A., Artigas-Arias, M., Alegría-Molina, A., Guerra-Vega, P., Navarrete, P., Venegas, Á., . . . Marzuca-Nassr, GN. (2023). Characterization of muscle mass, strength and mobility of critically ill patients with SARS-CoV-2 pneumonia: Distribution by sex, age, days on mechanical ventilation, and muscle weakness. Frontiers in Physiology. 14
[Journal article]Authored by: Vitzel, K.
Santos, AACD., Rodrigues, LE., Alecrim-Zeza, AL., de Araújo Ferreira, L., Trettel, CDS., Gimenes, GM., . . . Hirabara, SM. (2022). Molecular and cellular mechanisms involved in tissue-specific metabolic modulation by SARS-CoV-2. Frontiers in Microbiology. 13
[Journal article]Authored by: Vitzel, K.
de Vasconcelos, DAA., Nachbar, RT., Pinheiro, CH., do Amaral, CL., Crisma, AR., Vitzel, KF., . . . Leandro, CG. (2022). Maternal low-protein diet reduces skeletal muscle protein synthesis and mass via Akt-mTOR pathway in adult rats. Frontiers in Nutrition. 9
[Journal article]Authored by: Vitzel, K.
Marzuca-Nassr, GN., Kuwabara, WMT., Vitzel, KF., Murata, GM., Torres, RP., Mancini-Filho, J., . . . Curi, R. (2021). Endoplasmic reticulum stress and autophagy markers in soleus muscle disuse-induced atrophy of rats treated with fish oil. Nutrients. 13(7)
[Journal article]Authored by: Vitzel, K.
de Souza, DR., Vasconcelos, DAAD., Murata, GM., Fortes, MAS., Marzuca-Nassr, GN., Levada-Pires, AC., . . . Pithon-Curi, TC. (2020). Glutamine supplementation versus functional overload in extensor digitorum longus muscle hypertrophy. PharmaNutrition. 14
[Journal article]Authored by: Vitzel, K.
Hulton, AT., Vitzel, K., Doran, DA., & Maclaren, DPM. (2020). Addition of Caffeine to a Carbohydrate Feeding Strategy Prior to Intermittent Exercise. International Journal of Sports Medicine. 41(9), 603-609
[Journal article]Authored by: Vitzel, K.
Marzuca-Nassr, GN., Fortes, MAS., Guimarães-Ferreira, L., Murata, GM., Vitzel, KF., Vasconcelos, DAA., . . . Curi, R. (2019). Short-term creatine supplementation changes protein metabolism signaling in hindlimb suspension. Brazilian Journal of Medical and Biological Research. 52(10)
[Journal article]Authored by: Vitzel, K.
Norambuena-Mardones, L., Pinto-Daza, DE., Troncoso-Fernández, KD., Pacheco, A., Vitzel, KF., & Marzuca-Nassr, GN. (2019). Effectiveness of short-term physical agents treatment on macroscopic morphology in patients with plaque psoriasis. International Journal of Morphology. 37(4), 1541-1550
[Journal article]Authored by: Vitzel, K.
de Vasconcelos, DAA., Giesbertz, P., de Souza, DR., Vitzel, KF., Abreu, P., Marzuca-Nassr, GN., . . . Pithon-Curi, TC. (2019). Oral L-glutamine pretreatment attenuates skeletal muscle atrophy induced by 24-h fasting in mice. Journal of Nutritional Biochemistry. 70, 202-214
[Journal article]Authored by: Vitzel, K.
Marzuca-Nassr, GN., Vitzel, KF., Murata, GM., Márquez, JL., & Curi, R. (2019). Experimental Model of HindLimb Suspension-Induced Skeletal Muscle Atrophy in Rodents. 1916, 167-176
[Journal article]Authored by: Vitzel, K.
Guerra, MA., Caldas, LC., De Souza, HL., Vitzel, KF., Cholewa, JM., Duncan, MJ., . . . Guimarães-Ferreira, L. (2018). The acute effects of plyometric and sled towing stimuli with and without caffeine ingestion on vertical jump performance in professional soccer players. Journal of the International Society of Sports Nutrition. 15(1)
[Journal article]Authored by: Vitzel, K.
Araujo, TF., Cordeiro, AV., Vasconcelos, DAA., Vitzel, KF., & Silva, VRR. (2018). The role of cathepsin B in autophagy during obesity: A systematic review. Life Sciences. 209, 274-281
[Journal article]Authored by: Vitzel, K.
Marzuca-Nassr, GN., Vitzel, KF., Mancilla-Solorza, E., & Márquez, JL. (2018). Sarcomere structure: The importance of desmin protein in muscle atrophy. International Journal of Morphology. 36(2), 576-583
[Journal article]Authored by: Vitzel, K.
Fortes, MAS., Scervino, MVM., Marzuca-Nassr, GN., Vitzel, KF., da Justa Pinheiro, CH., & Curi, R. (2017). Hypertrophy stimulation at the onset of type I diabetes maintains the soleus but not the EDL muscle mass in Wistar rats. Frontiers in Physiology. 8(OCT)
[Journal article]Authored by: Vitzel, K.
Marzuca-Nassr, GN., Murata, GM., Martins, AR., Vitzel, KF., Crisma, AR., Torres, RP., . . . Curi, R. (2017). Balanced diet-fed fat-1 transgenic mice exhibit lower hindlimb suspension-induced soleus muscle atrophy. Nutrients. 9(10)
[Journal article]Authored by: Vitzel, K.
Serrano-Nascimento, C., Salgueiro, RB., Vitzel, KF., Pantaleão, T., Da Costa, VMC., & Nunes, MT. (2017). Iodine excess exposure during pregnancy and lactation impairs maternal thyroid function in rats. Endocrine Connections. 6(7), 510-521
[Journal article]Authored by: Vitzel, K.
Abreu, P., Vitzel, KF., Monteiro, ICCR., Lima, TI., Queiroz, AN., Leal-Cardoso, JH., . . . Ceccatto, VM. (2016). Effects of endurance training on reduction of plasma glucose during high intensity constant and incremental speed tests in wistar rats. Brazilian Journal of Medical and Biological Research. 49(11)
[Journal article]Authored by: Vitzel, K.
Pessoa, AFM., Florim, JC., Rodrigues, HG., Andrade-Oliveira, V., Teixeira, SA., Vitzel, KF., . . . Santos, MF. (2016). Oral administration of antioxidants improves skin wound healing in diabetic mice. Wound Repair and Regeneration. 24(6), 981-993
[Journal article]Authored by: Vitzel, K.
Marzuca-Nassr, GN., Vitzel, KF., De Sousa, LG., Murata, GM., Crisma, AR., Rodrigues Junior, CF., . . . Curi, R. (2016). Effects of high EPA and high DHA fish oils on changes in signaling associated with protein metabolism induced by hindlimb suspension in rats. Physiological Reports. 4(18)
[Journal article]Authored by: Vitzel, K.
Abreu, P., Pinheiro, CHJ., Vitzel, KF., Vasconcelos, DAA., Torres, RP., Fortes, MS., . . . Curi, R. (2016). Contractile function recovery in severely injured gastrocnemius muscle of rats treated with either oleic or linoleic acid. Experimental Physiology. 101(11), 1392-1405
[Journal article]Authored by: Vitzel, K.
Fortes, MAS., Marzuca-Nassr, GN., Vitzel, KF., Da Justa Pinheiro, CH., Newsholme, P., & Curi, R. (2016). Housekeeping proteins: How useful are they in skeletal muscle diabetes studies and muscle hypertrophy models?. Analytical Biochemistry. 504, 38-40
[Journal article]Authored by: Vitzel, K.
Fortes, MAS., Pinheiro, CHJ., Guimarães-Ferreira, L., Vitzel, KF., Vasconcelos, DAA., & Curi, R. (2015). Overload-induced skeletal muscle hypertrophy is not impaired in STZ-diabetic rats. Physiological Reports. 3(7)
[Journal article]Authored by: Vitzel, K.
Fortes, MS., Pinheiro, CJ., Guimaraes-Ferreira, L., Vitzel, KF., & Curi, R. (2013). Streptozotocin-induced diabetes does not impair overload-induced hypertrophy compared to control group in rat slow- and fast-twitch muscles.. MOLECULAR BIOLOGY OF THE CELL. 24
[Journal article]Authored by: Vitzel, K.
Pinheiro, CH., Fortes, MS., Guimaraes-Ferreira, L., Vitzel, KF., & Curi, R. (2013). Impaired myogenesis in skeletal muscle stem cells of diabetic mice. MOLECULAR BIOLOGY OF THE CELL. 24
[Journal article]Authored by: Vitzel, K.
Vitzel, KF., Bikopoulos, G., Hung, S., Pistor, KE., Patterson, JD., Curi, R., . . . Ceddia, RB. (2013). Chronic Treatment with the AMP-Kinase Activator AICAR Increases Glycogen Storage and Fatty Acid Oxidation in Skeletal Muscles but Does Not Reduce Hyperglucagonemia and Hyperglycemia in Insulin Deficient Rats. PLoS ONE. 8(4)
[Journal article]Authored by: Vitzel, K.
Vitzel, KF., Bikopoulos, G., Hung, S., Curi, R., & Ceddia, RB. (2013). Loss of the Anorexic Response to Systemic 5-Aminoimidazole-4-Carboxamide-1-β-D-Ribofuranoside Administration Despite Reducing Hypothalamic AMP-Activated Protein Kinase Phosphorylation in Insulin-Deficient Rats. PLoS ONE. 8(8)
[Journal article]Authored by: Vitzel, K.
Rodrigues, HG., Vinolo, MAR., Magdalon, J., Vitzel, K., Nachbar, RT., Pessoa, AFM., . . . Curi, R. (2012). Oral administration of oleic or linoleic acid accelerates the inflammatory phase of wound healing. Journal of Investigative Dermatology. 132(1), 208-215
[Journal article]Authored by: Vitzel, K.
Pinheiro, CHJ., Vitzel, KF., & Curi, R. (2012). Effect of N-acetylcysteine on markers of skeletal muscle injury after fatiguing contractile activity. Scandinavian Journal of Medicine and Science in Sports. 22(1), 24-33
[Journal article]Authored by: Vitzel, K.
da Pinheiro, CHJ., de Queiroz, JCF., Guimarães-Ferreira, L., Vitzel, KF., Nachbar, RT., de Sousa, LGO., . . . Curi, R. (2012). Local Injections of Adipose-Derived Mesenchymal Stem Cells Modulate Inflammation and Increase Angiogenesis Ameliorating the Dystrophic Phenotype in Dystrophin-Deficient Skeletal Muscle. Stem Cell Reviews and Reports. 8(2), 363-374
[Journal article]Authored by: Vitzel, K.
Da Justa Pinheiro, CH., Gerlinger-Romero, F., Guimarães-Ferreira, L., De Souza, AL., Vitzel, KF., Nachbar, RT., . . . Curi, R. (2012). Metabolic and functional effects of beta-hydroxy-beta-methylbutyrate (HMB) supplementation in skeletal muscle. European Journal of Applied Physiology. 112(7), 2531-2537
[Journal article]Authored by: Vitzel, K.
Guimarães-Ferreira, L., Pinheiro, CHJ., Gerlinger-Romero, F., Vitzel, KF., Nachbar, RT., Curi, R., . . . Nunes, MT. (2012). Erratum: Short-term creatine supplementation decreases reactive oxygen species content with no changes in expression and activity of antioxidant enzymes in skeletal muscle (European Journal of Applied Physiology DOI 10.1007/s00421-012-2378-9). European Journal of Applied Physiology. 112(11), 3913
[Journal article]Authored by: Vitzel, K.
Guimarães-Ferreira, L., Pinheiro, CHJ., Gerlinger-Romero, F., Vitzel, KF., Nachbar, RT., Curi, R., . . . Nunes, MT. (2012). Short-term creatine supplementation decreases reactive oxygen species content with no changes in expression and activity of antioxidant enzymes in skeletal muscle. European Journal of Applied Physiology. 112(11), 3905-3911
[Journal article]Authored by: Vitzel, K.
Silveira, LR., Pinheiro, CHDJ., Zoppi, CC., Hirabara, SM., Vitzel, KF., Bassit, RA., . . . Curi, R. (2011). Regulation of glucose and fatty acid metabolism in skeletal muscle during contraction. Arquivos Brasileiros de Endocrinologia e Metabologia. 55(5), 303-313
[Journal article]Authored by: Vitzel, K.
Newsholme, P., Abdulkader, F., Rebelato, E., Romanatto, T., Pinheiro, CHJ., Vitzel, KF., . . . Pithon-Curi, TC. (2011). Amino acids and diabetes: Implications for endocrine, metabolic and immune function. Frontiers in Bioscience. 16(1), 315-339
[Journal article]Authored by: Vitzel, K.
Nachbar, RT., Luchessi, AD., Cambiaghi, TD., Lambertucci, RH., Hirabara, SM., Vitzel, KF., . . . Curi, R. (2010). EFFECTS OF FATTY ACIDS ON PRODUCTION OF REACTIVE OXYGEN SPECIES (ROS) BY SKELETAL MUSCLE CELLS. FASEB JOURNAL. 24
[Journal article]Authored by: Vitzel, K.
Bassit, RA., Pinheiro, CHDJ., Vitzel, KF., Sproesser, AJ., Silveira, LR., & Curi, R. (2010). Effect of short-term creatine supplementation on markers of skeletal muscle damage after strenuous contractile activity. European Journal of Applied Physiology. 108(5), 945-955
[Journal article]Authored by: Vitzel, K.
Pinheiro, CHDJ., Silveira, LR., Nachbar, RT., Vitzel, KF., & Curi, R. (2010). Regulation of glycolysis and expression of glucose metabolism-related genes by reactive oxygen species in contracting skeletal muscle cells. Free Radical Biology and Medicine. 48(7), 953-960
[Journal article]Authored by: Vitzel, K.

Book

Vitzel, KF., Fortes, MA., Marzuca-Nassr, GN., Scervino, MVM., Pinheiro, CH., Silveira, LR., . . . Curi, R. (2018). In vivo electrical stimulation for the assessment of skeletal muscle contractile function in murine models. In Methods in Molecular Biology. (pp. 381 - 395).
[Chapter]Authored by: Vitzel, K.

Teaching and Supervision

Summary of Doctoral Supervision

Position Current Completed
Co-supervisor 6 0

Current Doctoral Supervision

Co-supervisor of:

  • Esther Elmi - Doctor of Philosophy
    Our Flow - increasing access to health-screening through menstrual blood, A Qualitative Ƶ
  • Shamirah Nabbosa - Doctor of Philosophy
    Effect of High Protein Beverage Supplementation and Resistance Training on Cardiovascular Health and Physical Function in Post-Ischemic Stroke Survivors.
  • Reder Mohammedsalih - Doctor of Philosophy
    The effect of beetroot juice supplementation on blood pressure in prehypertensive and hypertensive adults
  • Chamika Wickramaarachchi - Doctor of Philosophy
    Investigating occupational health, safety, and well-being outcomes among temporary migrants in the hospitality industry.
  • Henry Jones - Doctor of Philosophy
    Effect of dietary keratin protein supplementation on redox regulation of muscle insulin signalling and glucose transport.
  • Krutika Nanavati - Doctor of Philosophy
    Individual and additive effects of blackcurrant juice and caffeine intake on high intensity intermittent exercise performance