Journal
Chilton, B., Roach, RJ., Edwards, PJB., Jameson, GB., Hale, TK., & Filichev, VV. (2024). Inverted strand polarity yields thermodynamically stable G-quadruplexes and prevents duplex formation within extended DNA.
Chemical Science. 15(37), 15417-15431
[Journal article]Authored by: Edwards, P., Filichev, V., Hale, T., Jameson, G.Read article at Massey Research Online:
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Mitra, R., Fitzsimons, HL., Hale, T., Tan, ST., Gray, C., & White, MPJ. (2024). Recent advances in understanding the molecular basis of infantile haemangioma development.
British Journal of Dermatology. Advance access publication, Retrieved from https://academic.oup.com/bjd/advance-article/doi/10.1093/bjd/ljae241/7689274
[Journal article]Authored by: Fitzsimons, H., Hale, T.Read article at Massey Research Online:
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Harjes, S., Kurup, HM., Rieffer, AE., Bayarjargal, M., Filitcheva, J., Su, Y., . . . Jameson, GB. (2023). Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nature Communications. 14(1)
[Journal article]Authored by: Filichev, V., Hale, T., Jameson, G., Kurup, H.Read article at Massey Research Online:
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Schwartz, S., Wilson, SJ., Hale, TK., & Fitzsimons, HL. (2023). Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila.
Molecular Brain. 16(1)
[Journal article]Authored by: Fitzsimons, H., Hale, T., Wilson, S.Read article at Massey Research Online:
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Harjes, S., Kurup, HM., Rieffer, AE., Bayarjargal, M., Filichetva, J., Su, Y., . . . Jameson, GB. (2023). Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A.
Nature Communications. 14, Retrieved from https://www.nature.com/articles/s41467-023-42174-w
[Journal article]Authored by: Filichev, V., Hale, T., Jameson, G., Kurup, H.Read article at Massey Research Online:
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Harjes, S., Kurup, HM., Rieffer, AE., Bayaijargal, M., Filitcheva, J., Su, Y., . . . Jameson, GB. (2023). Structure-guided inhibition of the cancer DNA-mutating enzyme APOBEC3A..
Nature Communications. 14, Retrieved from https://www.nature.com/articles/s41467-023-42174-w
[Journal article]Authored by: Filichev, V., Hale, T., Jameson, G., Kurup, H.Read Online:
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Schwartz, S., Wilson, SJ., Hale, TK., & Fitzsimons, HL. (2023). Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila.
Molecular Brain. 16(1), Retrieved from https://molecularbrain.biomedcentral.com/articles/10.1186/s13041-023-01026-w
[Journal article]Authored by: Fitzsimons, H., Hale, T.Read article at Massey Research Online:
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Pradhan, S., Williams, MAK., & Hale, TK. (2022). Changes in the properties of membrane tethers in response to HP1α depletion in MCF7 cells.
Biochemical and Biophysical Research Communications. 587, 126-130
[Journal article]Authored by: Hale, T.Read Online:
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Pradhan, S., Solomon, R., Gangotra, A., Yakubov, GE., Willmott, GR., Whitby, CP., . . . Williams, MAK. (2021). Depletion of HP1α alters the mechanical properties of MCF7 nuclei.
Biophysical Journal. 120(13), 2631-2643
[Journal article]Authored by: Hale, T., Whitby, C.Read Online:
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Su, Y., Bayarjargal, M., Hale, TK., & Filichev, VV. (2021). DNA with zwitterionic and negatively charged phosphate modifications: Formation of DNA triplexes, duplexes and cell uptake studies.
Beilstein Journal of Organic Chemistry. 17, 749-761
[Journal article]Authored by: Filichev, V., Hale, T.Read article at Massey Research Online:
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Lukito, Y., Lee, K., Noorifar, N., Green, KA., Winter, DJ., Ram, A., . . . Scott, B. (2021). Regulation of host-infection ability in the grass-symbiotic fungus Epichloë festucae by histone H3K9 and H3K36 methyltransferases.
Environmental Microbiology. 23(4), 2116-2131 Retrieved from https://ami-journals.onlinelibrary.wiley.com/doi/10.1111/1462-2920.15370
[Journal article]Authored by: Hale, T.Read Online:
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Lukito, Y., Lee, K., Noorifar, N., Green, KA., Winter, DJ., Ram, A., . . . Scott, B. (2021). Regulation of host-infection ability in the grass-symbiotic fungus Epichloë festucae by histone H3K9 and H3K36 methyltransferases.
Environmental Microbiology. 23(4), 2116-2131
[Journal article]Authored by: Hale, T.Read Online:
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Lukito, Y., Lee, K., Noorifar, N., Green, K., Winter, D., Ram, A., . . . Scott, B. (2021). Regulation of host-infection ability in the grass-symbiotic fungus Epichloë festucae by histone H3K9 and H3K36 methyltransferases.
Environmental Microbiology. 23(4), 2116-2131 Retrieved from https://sfamjournals.onlinelibrary.wiley.com/doi/full/10.1111/1462-2920.15370
[Journal article]Authored by: Hale, T.Read Online:
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Roach, RJ., Garavís, M., González, C., Jameson, GB., Filichev, VV., & Hale, TK. (2020). Heterochromatin protein 1α interacts with parallel RNA and DNA G-quadruplexes.
Nucleic Acids Research. 48(2), 682-693
[Journal article]Authored by: Filichev, V., Hale, T., Jameson, G.Read Online:
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Lukito, Y., Chujo, T., Hale, TK., Mace, W., Johnson, LJ., & Scott, B. (2019). Regulation of subtelomeric fungal secondary metabolite genes by H3K4me3 regulators CclA and KdmB.
Molecular Microbiology. 112(3), 837-853
[Journal article]Authored by: Hale, T.Read Online:
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Doluca, O., Hale, TK., Edwards, PJB., González, C., & Filichev, VV. (2014). Assembly Dependent Fluorescence Enhancing Nucleic Acids in Sequence-Specific Detection of Double-Stranded DNA..
Chempluschem. 79(1), 2
[Journal article]Authored by: Edwards, P., Filichev, V., Hale, T.Read Online:
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Lasham, A., Moloney, S., Hale, T., Homer, C., Zhang, YF., Murison, JG., . . . Watson, J. (2003). The Y-box-binding protein, YB1, is a potential negative regulator of the p53 tumor suppressor.
Journal of Biological Chemistry. 278(37), 35516-35523
[Journal article]Authored by: Hale, T.Read Online:
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Hale, TK., Myers, C., Maitra, R., Kolzau, T., Nishizawa, M., & Braithwaite, AW. (2000). Maf transcriptionally activates the mouse p53 promoter and causes a p53- dependent cell death.
Journal of Biological Chemistry. 275(24), 17991-17999
[Journal article]Authored by: Hale, T.Read Online:
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Hale, TK., & Braithwaite, AW. (1999). The adenovirus oncoprotein E1a stimulates binding of transcription factor ETF to transcriptionally activate the p53 gene.
Journal of Biological Chemistry. 274(34), 23777-23786
[Journal article]Authored by: Hale, T.Read Online:
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Hale, TK., & Braithwaite, AW. (1995). Identification of an upstream region of the mouse p53 promoter critical for transcriptional expression.
Nucleic Acids Research. 23(4), 663-669
[Journal article]Authored by: Hale, T.Read Online:
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Ridgway, PJ., Hale, TK., & Braithwaite, AW. (1993). p53 confers a selective advantage on transfected HeLa cells.
Oncogene. 8(4), 1069-1074
[Journal article]Authored by: Hale, T.Read Abstract:
Hale, TK., Norris, GE., Jameson, GB., & Filichev, VV. (2014). Helicases, G4-DNAs, and drug design.
ChemMedChem. 9(9), 2031-2034
[Journal article]Authored by: Filichev, V., Hale, T., Jameson, G.Read Online:
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Tretiakova, MS., Bond, SD., Wheeler, D., Contreras, A., Kocherginsky, M., Kroll, TG., . . . Hale, TK. (2014). Heterochromatin protein 1 expression is reduced in human thyroid malignancy.
Laboratory Investigation. 94(7), 788-795
[Journal article]Authored by: Hale, T.Read Online:
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Park, JH., Hale, TK., Smith, RJ., & Yang, T. (2014). PPM1B depletion induces premature senescence in human IMR-90 fibroblasts.
Mechanisms of Ageing and Development. 138(1), 45-52
[Journal article]Authored by: Hale, T.Read Online:
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Doluca, O., Hale, TK., Edwards, PJB., Gonzalez, C., & Filichev, VV. (2014). Assembly dependent fluorescence enhancing nucleic acids in sequence-specific detection of double-stranded DNA.
ChemPlusChem. 79(1), 58-66
[Journal article]Authored by: Edwards, P., Filichev, V., Hale, T.Read Online:
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Clausell, J., Happel, N., Hale, TK., Doenecke, D., & Beato, M. (2009). Histone H1 subtypes differentially modulate chromatin condensation without preventing ATP-dependent remodeling by SWI/SNF or NURF.
PLoS ONE. 4(10)
[Journal article]Authored by: Hale, T.Read Online:
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Mandhan, P., Beasley, S., Hale, TK., Ellmers, L., Roake, J., & Sullivan, M. (2006). Sonic hedgehog expression in the development of hindgut in ETU-exposed fetal rats.
Pediatric Surgery International. 22, 31-36
[Journal article]Authored by: Hale, T.Read Online:
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Hale, TK., Contreras, A., Morrison, AJ., & Herrera, RE. (2006). Phosphorylation of the Linker Histone H1 by CDK Regulates Its Binding to HP1α.
Molecular Cell. 22(5), 693-699
[Journal article]Authored by: Hale, T.Read Online:
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Contreras, A., Hale, TK., Stenoien, DL., Rosen, JM., Mancini, MA., & Herrera, RE. (2003). The Dynamic Mobility of Histone H1 Is Regulated by Cyclin/CDK Phosphorylation.
Molecular and Cellular Biology. 23(23), 8626-8636
[Journal article]Authored by: Hale, T.Read Online:
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Hale, TK., & Mansfield, BC. (1989). Nucleotide sequence of a cDNA clone representing a third allele of human protein B23.
Nucleic Acids Research. 17(23), 10112
[Journal article]Authored by: Hale, T.
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Conference
Filichev, V., Jameson, G., Elena, H., & Hale, T. (2023, September). Inhibition of innate-immunity enzymes that are hijacked by cancer cells to evolve therapeutic resistance. Presented at
New Zealand Society of Oncology. Napier.
[Conference Oral Presentation]Authored by: Filichev, V., Hale, T., Jameson, G.
Hale, T. (2019, June). Heterochromatin Protein 1α interacts with parallel RNA and DNA G-quadruplexes. Presented at
Evolution, Structure and Function of Chromosomes High Order Structure Meeting. Institut Pasteur, Paris.
[Conference Oral Presentation]Authored by: Hale, T.
Lukito, Y., Noorifar, N., Green, K., Hale, T., Chujo, T., Johnson, L., . . . Scott, B. (2019).
The H3K9 and H3K36 methyltransferases ClrD and SetB regulate Epichloë festucae infection of perennial ryegrass. Poster session presented at the meeting of 30th Fungal Genetics Conference. Pacific Grove, CA
[Conference Poster]Authored by: Hale, T.
Lukito, Y., Chujo, T., Hale, T., Johnson, L., & Scott, B. (2018, June). H3K4 trimethylation mediated by CclA is a repressive mark for subtelomeric fungal secondary metabolite clusters that is removed by KdmB for derepression in planta. Presented at
ISFEG10. The 10th International Symposium on Fungal Endophytes of Grasses. Salamanca, Spain.
[Conference Oral Presentation]Authored by: Hale, T.
Hale, TK., & Solomon, R.Loss of HP1 alpha alters the integrity of the nuclear lamina, thereby promoting invasion.
CANCER RESEARCH. 78
(13)0008-5472.
[Conference]Authored by: Hale, T.
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Mandhan, P., Beasley, S., Hale, T., Ellmers, L., Roake, J., & Sullivan, M.Sonic hedgehog expression in the development of hindgut in ETU-exposed fetal rats.
Pediatric Surgery International. 22
(1)(pp. 31 - 36). 0179-0358.
[Conference]Authored by: Hale, T.Read Online:
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Hale, TK. (2017, November). Untethering the genome - Loss of HP1a enhances malignant cell invasion. Presented at
New Zealand Breast Cancer Symposium
[Conference Oral Presentation]Authored by: Hale, T.
Hale, TK., Bond, S., & Wheeler, D. (2017). Untethering heterochromatin: How loss of HP1a enhances cell invasion by altering nuclear envelope integrity [abstract]. In
Proceedings of the American Association for Cancer Research Annual Meeting 2017; 2017 Apr 1-5; Washington, DC. Philadelphia (PA): AACR; Cancer Research Vol. 77 , American Association of Cancer Research Annual Meeting: American Association for Cancer Research
[Conference Abstract]Authored by: Bond, S., Hale, T.Read Online:
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Lukito, Y., Chujo, T., Hale, TK., Johnson, LJ., & Scott, B. (2017).
Regulation of Epichloë festucae secondary metabolite genes by CclA, KdmB and H3K4 trimethylation. Poster session presented at the meeting of QMB Plant-Microbe Interactions Satellite at Queenstown Research Week
[Conference Poster]Authored by: Hale, T.
Lukito, Y., Chujo, T., Hale, TK., Johnson, LJ., & Scott, B.
Regulation of Epichloë festucae secondary metabolite genes by CclA, KdmB and H3K4 trimethylation. . Queenstown
[Conference Paper]Authored by: Hale, T.
Lukito, Y., Chujo, T., Hale, TK., Johnson, LJ., & Scott, B. (2017).
Regulation of Epichloë festucae secondary metabolite genes by CclA, KdmB and H3K4 trimethylation. Poster session presented at the meeting of QMB Plant-Microbe Interactions Satellite at Queenstown Research Week. Queenstown
[Conference Poster]Authored by: Hale, T.
Cui, X., Stimpson, L., Hale, T., & Contreras, A. (2016). Abstract 4538: Heterochromatin protein 1 alpha
modulates the invasive potential of malignant cells.
Cancer Research. Vol. 76: American Association of Cancer Research 107th Annual Meeting 2016;
[Conference Paper in Published Proceedings]Authored by: Hale, T.Read Online:
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Lukito, Y., Chujo, T., Hale, T., Johnson, L., & Scott, B. (2016). Histone H3K4 methylation regulates biosynthesis of fungal anti-mammalian alkaloids in an endophyte-plant symbiosis. , Third Cold Spring Harbor Laboratory Meeting on Epigenetics & Chromatin
[Conference Abstract]Authored by: Hale, T.
Cheng, L., Hale, TK., & Tretiakova, MS.Expression of Heterochromatin Protein 1 in Renal Cortical Tumors and Identification of Its Target Genes.
LABORATORY INVESTIGATION. (pp. 221A - 221A). 0023-6837.
[Conference]Authored by: Hale, T.
Cheng, L., Hale, TK., & Tretiakova, MS.(2016, February). Expression of Heterochromatin Protein 1 in renal cortical-tumors and identification of its target genes.
MODERN PATHOLOGY. (pp. 221A - 221A). 0893-3952.
[Conference]Authored by: Hale, T.
Bond, S., & Hale, TK. (2014).
Phosphorylation of Histone H1.4 by Aurora B is required for the proper execution of Mitosis. Poster session presented at the meeting of Gordon Conference on Chromatin Structure and Function, Boston, USA. Boston, United States of America
[Conference Poster]Authored by: Hale, T.Contributed to by: Hale, T.
Hale, TK. (2013, September). Heterochromatin Protein 1 in Cancer. Presented at
Queenstown Molecular Biology Meeting Epigenetics Satellite Meeting
[Conference Oral Presentation]Authored by: Hale, T.
Hale, TK. (2011, September). The role of histone H1 and HP1 in tumorigensis. Presented at
QMB Epigenetics Satellite Meeting. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Hale, T.Read Abstract:
Hale, TK., & Bond, S. (2010).
Aurora B Phosphorylates Histone H1 During Mitosis. Poster session presented at the meeting of Queenstown Molecular Biology Meeting. Queenstown, New Zealand
[Conference Poster]Authored by: Hale, T.Read Abstract:
Contreras, A., Gutierrez, MC., & Hale, TK.(2010, March). Differential Expression Patterns of the Heterochromatin Proteins HP1 alpha and HP1 beta in Different Tumor Types.
LABORATORY INVESTIGATION. (pp. 385A - 385A). 0023-6837.
[Conference]Authored by: Hale, T.
Contreras, A., Gutierrez, MC., & Hale, TK.(2010, March). Differential Expression Patterns of the Heterochromatin Proteins HP1 alpha and HP1 beta in Different Tumor Types.
MODERN PATHOLOGY. (pp. 385A - 385A). 0893-3952.
[Conference]Authored by: Hale, T.
Contreras, A., Gutierrez, M., & Hale, T. (2010). Differential expression patterns of the heterochromatin proteins HP1 and HP1β in different tumor types. In
United States and Canadian Academy of Pathology(pp. 385a - 385a). : Nature Publishing Group
[Conference Abstract]Authored by: Hale, T.
Hale, TK., & Contreras, A. (2009).
Is HP1 a Marker of Tumour Progression?. Poster session presented at the meeting of Abcam Chromatin Structure and Function Conference. Costa Rica
[Conference Poster]Authored by: Hale, T.Read Abstract:
Hale, TK., Purcell, R., Contreras, A., & Harte, J. (2008).
Genetic and epigenetic mechanisms in the pathogenesis of hepatoblastoma. Poster session presented at the meeting of Queenstown Molecular Biology Conference Epigenetics Meeting
[Conference Poster]Authored by: Hale, T.
Hale, TK. (2008, August). The role of the linker histone H1 and HP1 in heterochromatin and tumourigenesis. Presented at
QMB Epigenetics Satellite Meeting. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Hale, T.Read Abstract:
Hale, TK., Purcell, R., Sullivan, M., & Contreras, A. (2008).
The role of the linker histone H1 and HP1 in heterochromatin formation and cancer. Poster session presented at the meeting of New Zealand Society of Oncology Meeting. Christchurch, NZ
[Conference Poster]Authored by: Hale, T.Read Abstract:
Hale, TK. (2008).
The linker histone H1 and HP1 in hetercochromatin formation and cancer. Poster session presented at the meeting of NCI Genome-wide Chromatin Structure and Function Symposium. Washington DC, USA
[Conference Poster]Authored by: Hale, T.
Hale, TK. (2007, August). Histone H1 Phosphorylation in Chromatin Compaction and
Tumour Progression. Presented at
Queenstown Molecular Biology Conference. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Hale, T.Read Abstract:
Hale, TK., Sullivan, M., & Herrera, R. (2007).
The role of the linker histone H1 in epigenetic regulation and cancer. Poster session presented at the meeting of American Association for Cancer Research Annual Meeting. Los Angeles, USA (14-18 Apr 2007)
[Conference Poster]Authored by: Hale, T.Read Abstract:
Hale, TK., Purcell, R., & Contreras, A. (2007).
Investigating the role of the linker histone H1 in cancer. Poster session presented at the meeting of Abcam Chromatin Structure and Function Meeting. Antigua
[Conference Poster]Authored by: Hale, T.Read Abstract:
Hale, TK. (2006, August). The Linker Histone H1 and its Interaction with HP1. A Histone Code for H1. Presented at
Queenstown Molecular Biology Meeting. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Hale, T.Read Abstract:
Hale, TK. (2006, September). The Beginnings of a ‘Histone Code’ for the Linker Histone H1?. Presented at
Gene Expression & Chromatin Symposium. Ƶ, Albany.
[Conference Oral Presentation]Authored by: Hale, T.
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